What does LD50 refer to in toxicology?

LD50 refers to "Lethal Dose for 50% of subjects," which is a standard measurement used in toxicology to assess the toxicity of a substance. It indicates the dose of a toxic agent that is required to kill half of a defined population under controlled conditions. This metric is crucial in understanding the potency of a chemical and helps in evaluating the risk posed by exposure to various substances.

By determining the LD50, researchers can compare the toxicity of different compounds and establish safety guidelines for handling and disposing of hazardous materials. Understanding LD50 values is particularly important in regulatory contexts, as they assist in setting thresholds for allowable exposure levels in occupational and environmental settings.