What does NOEL stand for in toxicology?

NOEL stands for No Observed Effect Level in toxicology. This term is critical in risk assessment and toxicological studies as it refers to the highest concentration or dose of a substance that does not produce any observable adverse effects on the test subjects in a specific study. Establishing the NOEL is essential for determining safe exposure levels for humans and the environment. It helps regulatory agencies and scientists understand the potential risks associated with exposure to chemicals or pollutants, aiding in developing safety guidelines and regulations.

The concept of NOEL is an important factor in toxicology because it assists in identifying thresholds below which a substance is considered to be without harmful effects, thus offering a baseline for safe exposure. This is particularly valuable for environmental assessments, where understanding the impacts of pollutants on both ecological and human health is vital.