What is nephrotoxicity related to?

Nephrotoxicity specifically refers to the harmful effects of substances on the kidneys. This condition can result from exposure to various drugs, environmental toxins, or even certain medical conditions, leading to kidney damage or impaired function. The kidneys play a crucial role in filtering waste products from the blood, regulating fluid and electrolyte balance, and maintaining overall homeostasis in the body.

When the kidneys are affected by nephrotoxic agents, symptoms can manifest as decreased urine output, changes in urine composition, or elevations in blood urea nitrogen (BUN) and creatinine levels, indicating reduced kidney function. Understanding nephrotoxicity is essential for recognizing and addressing potential risks, especially in fields such as environmental engineering, where chemical exposure may significantly impact public health and safety.

Thus, recognizing nephrotoxicity as toxicity specifically related to the kidneys is critical for evaluating the health effects of various substances.